Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI)

Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI) - Names and Identifiers

Name	Ethanone, 2-chloro-1-(1H-indol-6-yl)-
Synonyms	6-(Chloroacetyl)-1H-indole 2-chloro-1-(1H-indol-6-yl)ethanone Ethanone, 2-chloro-1-(1H-indol-6-yl)- Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI) 2-Chloro-1-(1H-indol-6-yl)ethan-1-one, 6-(2-Chloroethanoyl)-1H-indole
CAS	123216-45-5

Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI) - Physico-chemical Properties

Molecular Formula	C10H8ClNO
Molar Mass	193.63
Density	1.337±0.06 g/cm3(Predicted)
Melting Point	128-129 °C(Solv: ethanol (64-17-5))
Boling Point	379.1±17.0 °C(Predicted)
pKa	15.56±0.30(Predicted)
Storage Condition	Room Temprature

Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI) - Introduction

2-Chloro-1-(1H-indol-6-yl)-ethanone is an organic compound with the chemical formula C10H8ClNO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-Chloro-1-(1H-indol-6-yl)-ethanone is a colorless to pale yellow liquid.
-Solubility: The compound can be dissolved in many organic solvents, such as methanol, ethanol and dichloromethane.
-Melting point and boiling point: The melting point range is about 75-77°C, and the boiling point range is about 245-248°C.

Use:
-2-Chloro-1-(1H-indol-6-yl)-ethanone is widely used in the field of organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds and is of great importance in the manufacture of pharmaceuticals and pesticides.

Preparation Method:
The preparation method of -2-chloro-1-(1H-indol-6-yl)-ethanone can use indole as a raw material and obtain it by reaction under alkaline conditions.
-A common preparation method is to react indole with bromoacetyl chloride in the presence of thionyl chloride.

Safety Information:
-2-Chloro-1-(1H-indol-6-yl)-ethanone is a chemical substance and should be used with caution.
-During the operation, direct contact with skin and eyes should be avoided, and good ventilation conditions should be maintained.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-During storage, the compound should be kept in a dry, cool, ventilated place, away from ignition and flammable substances.

Last Update：2024-04-09 15:17:51